The Implementing GeNomics In practice (IGNITE) Pragmatic Clinical Trials Network is an NIH-funded network dedicated to supporting the implementation of genomics in healthcare. Effective January 2022, Christina Wyatt, MD, associate professor of medicine (Nephrology) and Scott Palmer, MD, MHS, professor of medicine (Pulmonary, Allergy, and Critical Care Medicine) will replace Geoff Ginsburg, MD, PhD, as principal investigators for the IGNITE Pragmatic Clinical Trials Network coordinating center. Ginsburg recently was announced as the National Institutes of Health (NIH) Chief Medical and Scientific Officer for the All ...

  A Special Issue of the Journal of Personalized Medicine will present cutting-edge research and commentary to characterize the future of personalized medicine. Papers from multiple disciplinary perspectives focus on topics that have practical and policy relevance to help to advance the implementation of evidence-based innovation into routine healthcare. Please consider submitting a piece. Deadline for manuscript submission is April 20, 2022. Learn More and Submit. Contact Nina Sperber, PhD, Guest Editor, with questions (nina.sperber@duke.edu)

Abstract There is growing interest in utilizing pharmacogenetic (PGx) testing to guide antidepressant use, but there is lack of clarity on how to implement testing into clinical practice. We administered two surveys at 17 sites that had implemented or were in the process of implementing PGx testing for antidepressants. Survey 1 collected data on the process and logistics of testing. Survey 2 asked sites to rank the importance of Consolidated Framework for Implementation Research (CFIR) constructs using best-worst scaling choice experiments. ...

Lori Orlando, MD, MHS, MMCI, Director of the Precision Medicine Program in the Center for Applied Genomics and Precision Medicine at Duke University, recently contributed to the Duke Health blog on family health history. Did You know? Thanksgiving is also National Family Health History Day. Talk to your loved ones this holiday season. >>Read Story

The National Human Genome Research Institute (NHGRI) has produced this series of fact sheets to explain complex concepts in genomics research to a non-scientific audience. Teachers, students and the general public alike will find the materials clearly written and easy to understand. See more >>

Journal of Personalized Medicine recently published two papers featuring researchers from IGNITE Affiliate, Arkansas Children’s Hospital: Molecular Dysregulation in Autism Spectrum Disorder Implementing Pharmacogenomics Testing: Single Center Experience at Arkansas Children’s Hospital

Geoffrey Ginsburg, MD, PhD, a professor of Medicine (Cardiology), Pathology, Biostatistics and Bioinformatics, and Biomedical Engineering, and a professor in School of Nursing, will leave Duke to assume the role of Chief Medical and Scientific Officer for the National Institutes of Health (NIH) All of Us Research Program, effective January 2022. In this role, Dr. Ginsburg will help direct the national scientific research agenda to improve health and accelerate research using precision medicine. Dr. Ginsburg has been a visionary leader for Duke ...