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    • ADOPT PGx Depression Manuscript Published May 6, 2026

      A new manuscript from the IGNITE Pragmatic Trials Network has been published in JAMA Network Open, describing results from the ADOPT PGx Depression trial. The randomized clinical trial evaluated whether genotype-guided prescribing of selective serotonin reuptake inhibitors (SSRIs) could improve ...

    • GUARDD-US APOL1 Genetic Testing Manuscript Published March 6, 2026

      A new manuscript from the IGNITE Pragmatic Trials Network has been published in JAMA Network Open, describing the primary results of the GUARDD-US study.  GUARDD-US is a randomized controlled trial examining the impact of returning APOL1 genetic risk results to ...

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DCRI Think Tank Paper Looks to Future of Pragmatic Clinical Trials

DCRI Think Tank Paper Looks to Future of Pragmatic Clinical Trials

Posted on July 22, 2020August 28, 2020 by Alexis

Attendees to a January 2019 DCRI Think Tank outlined recommendations for optimizing pragmatic clinical trials and weighing risks and benefits of innovative trial designs.

Read more from the Duke Clinical Research Institute>>

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