The Lancet publishes series of 5 papers featuring IGNITE researchers

The fourth and fifth papers were released on August 5. One discusses the importance of family health history as a tool for risk assessment for common chronic diseases. The other reviews clinical outcome studies in genomic medicine and discusses the important features and key challenges to building evidence for next generation sequencing in the context of routine patient care.

Henry Ong to present at the AMIA 2019 Annual Symposium

Dr. Henry Ong will present his research, Extracting Drug Exposure Epochs and Drug Response Outcomes from Electronic Health Records, at the American Medical Informatics Association (AMIA) 2019 Annual Symposium on November 18. His research was selected out of a record number of submissions to AMIA this year -- over 1,200 across all categories!

Dr. Ong is a project manager in the IGNITE Network. He also serves as a project manager at the Vanderbilt Institute for Clinical and Translational Research. The AMIA 2019 Symposium will be held in Washington, D.C., November 16-20. This year's theme, Informatics: From Data to Knowledge to Action," will build on more than 40 years of sharing pioneering research and insights for leveraging information to improve human health.

NIH funds clinical trials using genomics to treat chronic diseases

The National Institutes of Health will fund clinical trials to assess the benefits, applicability and efficacy of applying genomic medicine interventions to improve management of diseases such as high blood pressure, depression and chronic pain. The trials are part of the second phase of the Implementing Genomics in Practice (IGNITE) Network with a total investment of $42 million over five years, pending the availability of funds. The trials will begin in 2020. Read more

NHGRI publishes overview about IGNITE

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Three IGNITE PIs presented at Precision Medicine Conference

Julie Johnson, PharmD, Carol Horowitz, M.D., M.P.H., and Josh Denny, M.D., were three of the presenters at the University of Florida Precision Medicine Conference, held March 6-7, 2019 in Orlando, Florida. This conference brings together clinicians, researchers and other thought leaders from medicine and pharmacy to receive cutting edge guidance from professionals with experience implementing genomic medicine and pharmacogenomics in a variety of settings.

PHASeR: A collaboration in PGx to help veterans

There are about 15 million cancer survivors in the United States; about 400,000 of them are also veterans in the Veterans Affairs (VA) system. As more people survive cancer, their medication needs go beyond their cancer treatment. For veterans, VA physicians hope to bring more personalization to cancer survivorship plans for patients with pharmacogenetic testing. Read more on CAGPM website

Evaluating Genomic Medicine Interventions

The IGNITE I Network funded six genomic medicine projects. Through varied interventions, Lori Orlando, M.D., and team hypothesized that synergies across projects could be leveraged to better understand participants’ experiences with genomic medicine interventions. The team performed cross-network analyses to identify associations between participant demographics and attitudes toward the intervention, plan to share results, and quality of life. Their results were published online on March 20, 2019, in Molecular Genetics & Genomic Medicine.

Ginsburg presented at 1st Macrogen and LKCMedicine Scientific Conference

Geoff Ginsburg, M.D., Ph.D., presented at the one-day scientific conference “Applications of Genomic Advances in Healthcare” on March 18, 2019, in Singapore. His presentation was entitled, “Achieving Impact of Precision Medicine Locally, Nationally and Internationally.”

The conference featured invited speakers from all over the world, including the United States, Finland, Germany, Thailand and Singapore to share their knowledge and experiences on how genomics can be applied to populations, pathways and people.