Implementing a pragmatic clinical trial to tailor opioids for chronic pain on behalf of the IGNITE ADOPT PGx investigators

Posted on by Alison Kilborn

Skaar TC, Myers RA, Fillingim RB, Callaghan JT, Cicali E, Eadon MT, Elwood EN, Ginsburg GS, Lynch S, Nguyen KA, Obeng AO, Park H, Pratt VM, Rosenman M, Sadeghpour A, Shuman S, Singh R, Tillman EM, Volpi S, Wiisanen K, Winterstein AG, Horowitz CR, Voora D, Orlando L, Chakraborty H, Van Driest S, Peterson JF, Cavallari LA, Johnson JA, Dexter PR

  • DOI: 10.1111/cts.70005

Rationale and design for a pragmatic randomized trial to assess gene-based prescribing for SSRIs in the treatment of depression

Posted on by Alison Kilborn

Hines LJ, Wilke RA, Myers R, Mathews CA, Liu M, Baye JF, Petry N, Cicali EJ, Duong BQ, Elwood E, Hulvershorn L, Nguyen K, Ramos M, Sadeghpour A, Wu RR, Williamson L, Wiisanen K, Voora D, Singh R, Blake KV, Murrough JW, Volpi S, Ginsburg GS, Horowitz CR, Orlando L, Chakraborty H, Dexter P, Johnson JA, Skaar TC, Cavallari LH, Van Driest SL, Peterson JF

  • DOI: 10.1111/cts.13822

Implementing a Pragmatic Clinical Trial to Tailor Opioids for Acute Pain on behalf of the IGNITE ADOPT PGx Investigators

Posted on by Alexis
Larisa H Cavallari, Emily Cicali, Kristin Wiisanen, Roger B Fillingim, Hrishikesh Chakraborty, Rachel A Myers, Kathryn V Blake, Bolanle Asiyanbola, Jordan F Baye, Wesley H Bronson, Kelsey J Cook, Erica N Elwood, Chancellor F Gray, Yan Gong, Lindsay Hines, Joseph Kannry, Natalie Kucher, Sheryl Lynch, Khoa A Nguyen, Aniwaa Owusu Obeng, Victoria M Pratt, Hernan A Prieto, Michelle Ramos, Azita Sadeghpour, Rajbir Singh, Marc Rosenman, Petr Starostik, Cameron D Thomas, Emma Tillman, Paul R Dexter, Carol R Horowitz, Lori A Orlando, Josh F Peterson, Todd C Skaar, Sara L Van Driest, Simona Volpi, Deepak Voora, Hari K Parvataneni, Julie A Johnson, The IGNITE Pragmatic Trials Network

Design and rationale of GUARDD-US: A pragmatic, randomized trial of genetic testing for APOL1 and pharmacogenomic predictors of antihypertensive efficacy in patients with hypertension

Posted on by Alexis
Michael T Eadon 1, Kerri L Cavanaugh 2, Lori A Orlando 3, David Christian 4, Hrishikesh Chakraborty 5, Kady-Ann Steen-Burrell 6, Peter Merrill 6, Janet Seo 4, Diane Hauser 7, Rajbir Singh 8, Cherry Maynor Beasley 9, Jyotsna Fuloria 10, Heather Kitzman 11, Alexander S Parker 12, Michelle Ramos 4, Henry H Ong 2, Erica N Elwood 13, Sheryl E Lynch 1, Sabrina Clermont 4, Emily J Cicali 13, Petr Starostik 14, Victoria M Pratt 1, Khoa A Nguyen 13, Marc B Rosenman 15, Neil S Calman 7, Mimsie Robinson 16, Girish N Nadkarni 17, Ebony B Madden 18, Natalie Kucher 18, Simona Volpi 18, Paul R Dexter 1, Todd C Skaar 1, Julie A Johnson 13, Rhonda M Cooper-DeHoff 19, Carol R Horowitz 20, GUARDD-US Investigators

Effects of Testing and Disclosing Ancestry-Specific Genetic Risk for Kidney Failure on Patients and Health Care Professionals: A Randomized Clinical Trial

Posted on by Alison Kilborn

Nadkarni, G. N., Fei, K., Ramos, M. A., Hauser, D., Bagiella, E., Ellis, S. B., Sanderson, S., Scott, S. A., Sabin, T., Madden, E., Cooper, R., Pollak, M., Calman, N., Bottinger, E. P., & Horowitz, C. R.

CYP2C19 Genotype-Guided Antiplatelet Therapy After Percutaneous Coronary Intervention in Diverse Clinical Settings

Posted on by Alexis

Amber L Beitelshees 1, Cameron D Thomas 2, Philip E Empey 3, George A Stouffer 4, Dominick J Angiolillo 5, Francesco Franchi 5, Sony Tuteja 6, Nita A Limdi 7, James C Lee 8, Julio D Duarte 2, Rolf P Kreutz 9, Todd C Skaar 9, James C Coons 3, Jay Giri 10, Caitrin W McDonough 2, Rachel Rowland 1, James M Stevenson 3 11, Thuy Thai 12, Mark R Vesely 1, Jacob T Wellen 1, Julie A Johnson 2, Almut G Winterstein 12, Larisa H Cavallari 2, Craig R Lee 4 13, Implementing Genomics in Practice (IGNITE) Network Pharmacogenetics Working Group

PMID: 35156424 DOI: 10.1161/JAHA.121.024159