Publication | Ignite II

Moving Pharmacogenetics into Practice: It’s All About the Evidence!

Posted on June 16, 2021June 16, 2021 by Alexis

Luzum JA, Petry N, Taylor AK, Van Driest SL, Dunnenberger HM, Cavallari LH. Clin Pharmacol Ther. 2021 Jun 8. doi: 10.1002/cpt.2327. Online ahead of print. PMID: 34101169 Review.

Determining the potential clinical value of panel-based pharmacogenetic testing in patients with chronic pain or gastroesophageal reflux disease

Posted on June 16, 2021 by Alexis

Elchynski AL, Cicali EJ, Ferrer Del Busto MC, Hamilton A, Chang KL, Schmidt SO, Weiner B, Davis R, Estores D, Max Smith D, Wiisanen K, Johnson JA, Cavallari LH.

Pharmacogenomics J. 2021 Jun 1. doi: 10.1038/s41397-021-00244-6. Online ahead of print.

PMID: 34075203

Multi-Institutional Implementation of Clinical Decision Support for APOL1, NAT2, and YEATS4 Genotyping in Antihypertensive Management.

Posted on June 16, 2021June 21, 2024 by Alexis

Schneider TM, Eadon MT, Cooper-DeHoff RM, Cavanaugh KL, Nguyen KA, Arwood MJ, Tillman EM, Pratt VM, Dexter PR, McCoy AB, Orlando LA, Scott SA, Nadkarni GN, Horowitz CR, Kannry JL.

J Pers Med. 2021 May 27;11(6):480. doi: 10.3390/jpm11060480.

PMID: 34071920

PharmVar GeneFocus: CYP2C9

Posted on June 10, 2021October 20, 2021 by Alexis

Sangkuhl K, Claudio-Campos K, Cavallari LH, Agundez J, Whirl-Carrillo M, Duconge J, Del Tredici AL, Wadelius M, Botton MR, Woodahl EL, Scott SA, Klein TE, Pratt VM, Daly AK, Gaedigk A. Clin Pharmacol Ther. 2021 Jun 10. doi: 10.1002/cpt.2333.

Online ahead of print.

PMID: 34109627 Review.

Establishing the value of genomics in medicine: the IGNITE Pragmatic Trials Network

Posted on March 30, 2021June 21, 2024 by Alexis

A critical gap in the adoption of genomic medicine into medical practice is the need for the rigorous evaluation of the utility of genomic medicine interventions.

Opportunity for Genotype-Guided Prescribing Among Adult Patients in 11 US Health Systems

Posted on January 11, 2021June 21, 2024 by Alexis

J. Kevin Hicks, Nihal El Rouby,Henry H. Ong, Jonathan S. Schildcrout, Laura B. Ramsey, Yaping Shi,Leigh Anne Tang, Christina L. Aquilante,Amber L. Beitelshees, Kathryn V. Blake, James J. Cimino,Brittney H. Davis, Philip E. Empey, David P. Kao,Daniel L. Lemkin, Nita A. Limdi, Gloria P. Lipori, Marc B. Rosenman, Todd C. Skaar, Evgenia Teal, Sony Tuteja, Laura K. Wiley, Helen Williams, Almut G. Winterstein, Sara L. Van Driest, Larisa H. Cavallari, Josh F. Peterson, on behalf of the IGNITE Pharmacogenetics Working Group

First published: 11 January 2021 https://doi.org/10.1002/cpt.2161

Prescribing Prevalence of Medications With Potential Genotype-Guided Dosing in Pediatric Patients

Posted on December 14, 2020June 21, 2024 by Alexis

Laura B. Ramsey, PhD^1,2; Henry H. Ong, PhD³; Jonathan S. Schildcrout, PhD⁴; Yaping Shi, MS⁴; Leigh Anne Tang, BS⁵; J. Kevin Hicks, PharmD, PhD⁶; Nihal El Rouby, PharmD, PhD^7,8; Larisa H. Cavallari, PharmD⁷; Sony Tuteja, PharmD, MS⁹; Christina L. Aquilante, PharmD¹⁰; Amber L. Beitelshees, PharmD, MPH¹¹; Daniel L. Lemkin, MD, MS¹²; Kathryn V. Blake, PharmD¹³; Helen Williams, BS¹⁴; James J. Cimino, MD¹⁵; Brittney H. Davis, PharmD¹⁶; Nita A. Limdi, PharmD, PhD, MPSH¹⁶; Philip E. Empey, PharmD, PhD¹⁷; Christopher M. Horvat, MD, MHA¹⁸; David P. Kao, MD¹⁹; Gloria P. Lipori, MT, MBA²⁰; Marc B. Rosenman, MD^21,22; Todd C. Skaar, PhD²³; Evgenia Teal, MA²⁴; Almut G. Winterstein, PhD²⁵; Aniwaa Owusu Obeng, PharmD²⁶; Daria Salyakina, PhD²⁷; Apeksha Gupta, MPH²⁷; Joshua Gruber, MPH²⁷; Jennifer McCafferty-Fernandez, PhD²⁷; Jeffrey R. Bishop, PharmD, MS^28,29; Zach Rivers, PharmD³⁰; Ashley Benner, MPH³¹; Bani Tamraz, PharmD, PhD³²; Janel Long-Boyle, PharmD, PhD³²; Josh F. Peterson, MD, MPH³³; Sara L. Van Driest, MD, PhD^33,34; for the IGNITE Pharmacogenetics Working Group

JAMA Netw Open. 2020;3(12):e2029411. doi:10.1001/jamanetworkopen.2020.29411

Impact of the CYP2C19*17 Allele on Outcomes in Patients Receiving Genotype-Guided Antiplatelet Therapy After Percutaneous Coronary Intervention

Posted on September 8, 2020June 21, 2024 by Alexis

Craig R. Lee,Cameron D. Thomas,Amber L. Beitelshees,Sony Tuteja,Philip E. Empey,James C. Lee,Nita A. Limdi,Julio D. Duarte,Todd C. Skaar,Yiqing Chen,Kelsey J. Cook,James C. Coons,Chrisly Dillon,Francesco Franchi,Jay Giri,Yan Gong,Rolf P. Kreutz,Caitrin W. McDonough,James M. Stevenson,Karen E. Weck,Dominick J. Angiolillo,Julie A. Johnson,George A. Stouffer,Larisa H. Cavallari, on behalf of the IGNITE Network Pharmacogenetics Working Group

First published: 08 September 2020 https://doi.org/10.1002/cpt.2039

Affiliate network members as force amplifiers of genomic medicine research

Posted on November 11, 2019October 8, 2020 by Alexis

Future Medicine — The Implementing GeNomics In pracTicE (IGNITE) Network is an NIH-funded network dedicated to advancing the implementation of genomics in healthcare.

Pharmacogenomics competencies in pharmacy practice: A blueprint for change

Posted on August 16, 2019October 8, 2020 by Alexis

Journal of the American Pharmacists Association – The emerging use of genomic data to inform medication therapy populates the medical literature and provides evidence for guidelines in the prescribing information for many medications.