Henry Ong to present at the AMIA 2019 Annual Symposium

Dr. Henry Ong will present his research, Extracting Drug Exposure Epochs and Drug Response Outcomes from Electronic Health Records, at the American Medical Informatics Association (AMIA) 2019 Annual Symposium on November 18. His research was selected out of a record number of submissions to AMIA this year — over 1,200 across all categories!

Dr. Ong is a project manager in the IGNITE Network. He also serves as a project manager at the Vanderbilt Institute for Clinical and Translational Research. The AMIA 2019 Symposium will be held in Washington, D.C., November 16-20. This year’s theme, Informatics: From Data to Knowledge to Action,” will build on more than 40 years of sharing pioneering research and insights for leveraging information to improve human health.

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The Role of Digital Health Technologies in Drug Development: A Workshop

This workshop will provide a venue to discuss challenges and opportunities in digital health technologies for improving the probability of success in drug development and enabling precision medicine. Workshop participants may consider key components for an evidence-based framework for applying digital health technologies towards drug research and development.

When: Tuesday, March 24, 2020; 10 a.m. – 4:15 p.m..
Where: Webinar only; Registration required

Genomic and Precision Medicine Weekly Forum

Svati Shah, M.D., MHS
Associate Dean of Genomics and Director, Duke Precision Genomics Collaboratory; Professor of Medicine; Director, Adult Cardiovascular Genetics Clinic
Duke University

When: March 19, 2020
Where: WebEx

Genomic and Precision Medicine Weekly Forum

Bryce Seifert, Ph.D.
ABMGG Laboratory Genetics and Genomics Fellow
Duke University
Clinical Validity Assessment of Genes Frequently Tested on Hereditary Cancer Susceptibility Sequencing Panels

When: March 5, 2020
Where: Duke University

5th Annual Precision Medicine Conference

A two-day series of interactive presentations and panel sessions will feature some of the nation’s leading experts on emerging topics in genomic medicine and pharmacogenomics.

When: Friday February 21 – Saturday, February 22, 2020
Where: Orlando, FL

Genomic and Precision Medicine Weekly Forum

Calum MacRae, M.D., Ph.D.
Vice Chair for Scientific Innovation, Brigham and Women’s Hospital; Associate Professor of Medicine
Harvard Medical School
Overcoming the barriers to clinical whole genome sequencing in routine acute care

When: February 20, 2020
Where: Duke University

Clinical Pharmacogenomics Preconference

These sessions will provide the latest update on emerging topics in pharmacogenomics. Attendees will learn from pharmacogenomics implementation leaders about their real world-experiences with using pharmacogenomics in the clinic, describe the regulatory oversight and need for evidence-based pharmacogenomic testing, as well as discuss the hottest topics in clinical pharmacogenomics today. The inaugural Clinical Pharmacogenomics Networking Reception to immediately follow.

When: Thursday, February 20, 2020
Where: Orlando, FL

Stakeholder Summit: Federal Regulation of Pharmacogenomic Testing

UF Precision Medicine Program and Precision Medicine Advisors will bring together stakeholders to discuss recent regulation by the FDA and formulate solutions for improving the safety and efficacy of pharmacogenomic tests.

When: Thursday, February 20, 2020; 8 a.m. – noon
Where: Orlando, FL

Genomic and Precision Medicine Weekly Forum

Elizabeth McNally, M.D., Ph.D.
Director, Center for Genetic Medicine; Professor of Medicine and Biochemistry and Molecular Genetics
Northwestern University
Genetic Variation In Heart Failure: From Rare to Common and In Between

When: February 13, 2020
Where: Duke University

Genomic and Precision Medicine Weekly Forum

Rebekah Ryanne Wu, M.D.
Assistant Professor of Medicine
Duke University
Impact of Family Health History on Understanding Genomic Risk in Singaporean Populations

When: February 6, 2020
Where: Duke University

Genomic and Precision Medicine Weekly Forum

Isaac Kohane, M.D., Ph.D.
Chair, Department of Biomedical Informatics; Professor of Biomedical Informatics
Harvard Medical School
What Can We Learn from Genomics Being the Leading Application of Clinical AI?

When: January 30, 2020
Where: Duke University

Precision Medicine World Conference

PMCW is the largest annual conference dedicated to precision medicine and brings together recognized leaders, top global researchers and medical professionals, and innovators across healthcare and biotechnology sectors.

When: January 21 – 24, 2020
Where: Silicon Valley, CA
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Genomic and Precision Medicine Weekly Forum

Cynthia Moylan, M.D.
Associate Professor of Medicine
Duke University
The Looming NASH Epidemic: Using -omics for risk stratification and prevention

When: January 23, 2020
Where: Duke University

IGNITE Steering Committee Meeting

IGNITE will conduct a a two-day Steering Committee Meeting

When: Wednesday, January 22 – Thursday, January 23, 2020
Where: University of Florida Research & Academic Center, Lake Nona, FL

Genomic and Precision Medicine Weekly Forum

Joe Grzymski, Ph.D.
Senior Director, Applied Innovation Center; Associate Research Professor of Microbiology and Computational Biology
Desert Research Institute
The Healthy Nevada Project Genetics Study and Linking Phenotype to Genotype

When: January 16, 2020
Where: Duke University

Genomic and Precision Medicine Weekly Forum

Lisa Bastarache, M.S.
Research Assistant Professor
Vanderbilt University Medical Center
How much more can we explain with genetics? Using EHRs to find Undiagnosed Patients

When: January 9, 2020
Where: Duke University

Genomic and Precision Medicine Weekly Forum

Opeyemi Olabisi, M.D., Ph.D.
Assistant Professor of Medicine, Division of Nephrology
Duke University
Patient-stem cell-derived podocytes as tools for modeling APOL1-associated kidney disease

When: Thursday, December 19, 2019, noon – 1 P.M.
Where: Duke University

Therapeutic Genome Editing: An ASHG-AJHG Webinar

Advances in the technology of genome editing offer major opportunities in the treatment of genetic disorders, but also raise complex technical and ethical issues. This webinar will explore these considerations both for somatic and germline genome editing and will explore the future research agenda for therapeutic genome editing.

When: Wednesday, December 11, 2 – 3 P.M.

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Genomic and Precision Medicine Weekly Forum

George Church, Ph.D.
Professor of Genetics; Director, PersonalGenomes.org; Harvard University
Reading and Writing Omes

When: Thursday, December 5, 2019, noon – 1 P.M.
Where: Duke University

Precision Medicine Insights: A Webinar Series

Kristin Wiisanen, Pharm.D., FAPhA

When: Tuesday, December 3, 2019, 12 p.m. EDT

University of Florida precision medicine leaders will highlight current knowledge and trends in this series, including professional and educational opportunities, to advance the future of health care. Join us as Dr. Kristin Wiisanen, online graduate program director, discusses challenges and approaches to patient education in the era of precision medicine.

AMIA 2019 Annual Symposium

Under the overall theme of “Informatics: From Data to Knowledge to Action” the Ameican Medical Informatics Association (AMIA) Annual Symposium will build on more than 40 years of sharing pioneering research and insights for leveraging information to improve human health.

When: Saturday, Nov. 16 – Wednesday, Nov. 20, 2019
Where: Washington, D.C.

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15th Annual Personalized Medicine Conference

The 15th Annual Personalized Medicine Conference will convene the world’s leading researchers, investors, industry executives, policy experts, payers, clinicians, and patient advocates to define the landscape and outlook for personalized medicine in science, business, and policy.

When: Wednesday, Nov. 13 – Thursday, Nov. 14, 2019
Where: Boston, MA

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Genomic and Precision Medicine Weekly Forum

Hakon Hakonarson, M.D., Ph.D.
Director, Center for Applied Genomics at the Joseph Stokes Jr. Research Institute; Professor of Pediatrics; Children’s Hospital of Philadelphia

When: Thursday, November 7, 2019, noon – 1 P.M.
Where: Duke University

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Genomic and Precision Medicine Weekly Forum

Rhoda Au, Ph.D.
Professor of Anatomy & Neurobiology; Boston University

When: Thursday, October 31, 2019, noon – 1 P.M.
Where: Duke University

Exploring the Current Landscape of Consumer Genomics – A Workshop

The Roundtable on Genomics and Precision Health will host a one day public workshop to explore the current landscape of consumer genomics and implications for how genetic test information is used or may be used in research and clinical care.

When: Tuesday, October 29, 2019, 8:30 A.M.
Where: Washington, D.C.

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Genomic and Precision Medicine Weekly Forum

Gregory Gray, M.D., MPH, FIDSA
Professor of Medicine, Global Health and Environmental Health; Duke University

When: Thursday, October 24, 2019, noon – 1 P.M.
Where: Duke University

American Society of Human Genetics 2019 Annual Meeting

ASHG 2019 featured invited presentations by the world’s leading geneticists, in addition to symposia, workshops, and abstract-driven sessions about new developments in basic, translational, and clinical human genetics research and technology.

When: Tuesday, October 15 – Saturday, October 19, 2019
Where: Houston, Tx

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Genomic and Precision Medicine Weekly Forum

Joanne Ngeow, MBBS, MRCP, MPH
Senior Consultant, Division of Medical Oncology, National Cancer Centre Singapore

When: Thursday, October 10, 2019, noon – 1 P.M.
Where: Duke University

Genomic and Precision Medicine Weekly Forum

Brian Sullivan, M.D.
Medical Instructor in the Department of Medicine; Duke University

When: Thursday, October 3, 2019, noon – 1 P.M.
Where: Duke University

NHGRI Stategic Planning Workshop

Genomics in Medicine & Health

NHGRI is in the middle of a new round of strategic planning that will establish a ‘2020 vision for genomics’ and culminate in the publication of a new NHGRI strategic plan in October 2020 and is soliciting input from the broader research and public communities to help shape the 2020 strategic plan.

When: Thursday, Sept. 26 – Friday, Sept. 27, 2019, 8 A.M. – 5 P.M. both days
Where: Bethesda, MD

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Enhancing Scientific Reproducibility through Transparent Reporting – A Workshop

An ad hoc committee of the National Academies of Sciences, Engineering, and Medicine convened a public workshop to discuss the current state of transparency in reporting pre-clinical biomedical research and to explore the possibility of improving the harmonization of guidelines across journals and funding agencies so that biomedical researchers propose and report data in a consistent manner.

When: Wednesday, September 25 – Thursday, September 26, 2019; 8:30 A.M.
Where: Washington, D.C.

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IGNITE Steering Committee Meeting

IGNITE conducted a a two-day Steering Committee Meeting and joint meeting with the Data and Safety Monitoring Board

When: Wednesday, September 25 – Thursday, September 26, 2019
Where: Silver Spring, MD

Genomic and Precision Medicine Weekly Forum

Richard Gibbs, Ph.D.
Director, Human Genome Sequencing Center; Professor of Translational Biology & Molecular Medicine and Integrative Molecular and Biomolecular Sciences; Baylor College of Medicine

When: Thursday, September 19, 2019, noon – 1 P.M.
Where: Duke University

Genomic and Precision Medicine Weekly Forum

Georgia Wiesner, Ph.D.
Professor of Medicine, Vanderbilt University

When: Thursday, September 12, 2019, noon – 1 P.M.
Where: Duke University

IGNITE Steering Committee Meeting

IGNITE conducted a a two-day Steering Committee Meeting

When: Thursday, July 25 – Friday, July 26, 2019
Where: Orlando, Florida

NIH Collaboratory Grand Rounds

Moving Beyond Return of Research Results to Return of Value

Speaker: Consuelo H. Wilkins, M.D., MSCI
Vice President for Health Equity, Vanderbilt University Medical Center
Executive Director, Meharry-Vanderbilt Alliance

When: Friday, June 28, 1 – 2 P.M. EST

NIH Collaboratory Grand Rounds

Good Clinical Practice Guidance and Pragmatic Trials: Balancing the Best of Both Worlds in the Learning Health System

Speaker: Robert J. Mentz, M.D., FACC, FAHA, FHFSA
Director of the Duke Cooperative Cardiovascular Society
Assistant Program Director of the Duke Cardiovascular Disease Fellowship
Associate Professor
Duke University Medical Center and Duke Clinical Research Institute

When: Friday, June 14, 1 – 2 P.M. EST
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NIH funds clinical trials using genomics to treat chronic diseases

The National Institutes of Health will fund clinical trials to assess the benefits, applicability and efficacy of applying genomic medicine interventions to improve management of diseases such as high blood pressure, depression and chronic pain. The trials are part of the second phase of the Implementing Genomics in Practice (IGNITE) Network with a total investment of $42 million over five years, pending the availability of funds. The trials will begin in 2020. Read more

NHGRI publishes overview about IGNITE

The Implementing Genomic in Practice (IGNITE) Network was established in 2013 (RFA-HG-12-006RFA-HG-12-007 and RFA-HG-13-004) to develop methods for incorporating genomic information into clinical care and explore the methods for effective implementation, diffusion, and sustainability in diverse clinical settings. The first phase of the network, IGNITE I, was a consortium of collaborative genomic medicine pilot Demonstration Projects designed to demonstrate the feasibility of, and develop methods for, incorporating an individual patient’s genomic findings into his or her clinical care.

The next phase of IGNITE, IGNITE II (RFA-HG-17-008RFA-HG-17-009, and RFA-HG-17-010) will support a network of multi-site Clinical Groups (CGs) involving diverse settings and populations to conduct 2-3 pragmatic clinical trials of genomic medicine interventions.

Read full overview from NIH

PHASeR: A collaboration in PGx to help veterans

There are about 15 million cancer survivors in the United States; about 400,000 of them are also veterans in the Veterans Affairs (VA) system. As more people survive cancer, their medication needs go beyond their cancer treatment. For veterans, VA physicians hope to bring more personalization to cancer survivorship plans for patients with pharmacogenetic testing. Read more on CAGPM website

Evaluating Genomic Medicine Interventions

The IGNITE I Network funded six genomic medicine projects. Through varied interventions, Lori Orlando, M.D., and team hypothesized that synergies across projects could be leveraged to better understand participants’ experiences with genomic medicine interventions. The team performed cross-network analyses to identify associations between participant demographics and attitudes toward the intervention, plan to share results, and quality of life. Their results were published online on March 20, 2019, in Molecular Genetics & Genomic Medicine.

Ginsburg presented at 1st Macrogen and LKCMedicine Scientific Conference

Geoff Ginsburg, M.D., Ph.D., presented at the one-day scientific conference “Applications of Genomic Advances in Healthcare” on March 18, 2019, in Singapore. His presentation was entitled, “Achieving Impact of Precision Medicine Locally, Nationally and Internationally.”

The conference featured invited speakers from all over the world, including the United States, Finland, Germany, Thailand and Singapore to share their knowledge and experiences on how genomics can be applied to populations, pathways and people.

Three IGNITE PIs presented at Precision Medicine Conference

Julie Johnson, PharmD, Carol Horowitz, M.D., M.P.H., and Josh Denny, M.D., were three of the presenters at the University of Florida Precision Medicine Conference, held March 6-7, 2019 in Orlando, Florida. This conference brings together clinicians, researchers and other thought leaders from medicine and pharmacy to receive cutting edge guidance from professionals with experience implementing genomic medicine and pharmacogenomics in a variety of settings.