2024 Precision Medicine Tri-Conference

2024 Precision Medicine Tri-Conference

March 26-28 | San Diego, CA

Join thousands of international thought leaders to discuss the latest research, technologies, innovation and business models in precision medicine and precision health. Topics will include innovation and market access strategies for at-home diagnostics, liquid biopsy and advanced diagnostics for precision oncology, AI and digital tools, spatial biology and single-cell multiomics in advancing precision medicine and more.

To learn more and register, visit the conference website.

Please note: Registration is required for both in-person and virtual attendees.

2024 ACMG Annual Clinical Genetics Meeting

2024 ACMG Annual Clinical Genetics Meeting

March 12-16 | Toronto, Canada

The ACMG sponsors an Annual Clinical Genetics Meeting and other events offering educational content in clinical genetics with the purpose of serving its members, other healthcare professionals and the public. Experience the transformation of medical genetics as treatments can increasingly be tailored with precision medicine and therapeutics.

To learn more and register, visit the meeting website.

Please note: Registration is required for in-person attendance and does not include session recordings. ACMG’s Digital Edition for recordings can be purchased separately and will be made available after the conference.

An Overview of Applied Machine Learning in Medicine at UNC

An Overview of Applied Machine Learning in Medicine at UNC

Thursday, January 4 | 12-1 p.m. ET | 4th Floor Old Clinic Auditorium or Online

Speaker: Amanda Nelson, MD
Associate Professor of Medicine, UNC-Chapel Hill

A discussion on the application of AI tools to answer clinical questions around diagnosis, phenotyping, prognosis, and precision medicine using examples from investigators at UNC.

 

WebEx Information:

https://uncsom.webex.com/uncsom/j.php?MTID=m893f54367d9d2ac90bbac612e815bf88
Meeting number (access code): 2314 463 7243
Meeting password: V!rtu@lmgr22

Carolina Seminar Series | Precision Medicine Research and Novel Clinical Offerings: Ensuring Equitable Impact Through Implementation Science

Precision Medicine Research and Novel Clinical Offerings: Ensuring Equitable Impact Through Implementation Science

Wednesday, December 6 | 4 p.m. ET | Online

Speakers: Caitlin Allen, PhD, MPH
Assistant Professor, Medical University of South Carolina

Elizabeth Mayer-Davis, PhD, RD
Boshamer Distinguished Professor of Nutrition and Medicine, UNC-Chapel Hill

As technologies and health interventions expand at a rapid rate in healthcare, many providers and patients desire quick and efficient incorporation of these new offerings in to practice.  The field of implementation science can be critical in studying the barriers and facilitators to bring options previously available only in the research realm to the clinic. The design and development of health interventions are increasingly informed by implementation science theories, models, and frameworks to emphasize diverse reach and improve adoption and increase health equity in under served and marginalized communities. By testing new clinical offerings with implementation science methodologies, we can improve the quality of health practices for all patients while promoting equity and inclusion and ensuring that the availability of novel clinical offerings does not exacerbate existing health disparities.

To learn more and register, visit the UNC events page.

Please note: Registration is required for this seminar.

Precision Medicine and Immunotherapy: The new frontiers in cancer care?

Precision Medicine and Immunotherapy: The new frontiers in cancer care?

Friday, November 10 | 11 a.m. ET | Online

Speaker: Ugwuji Maduekwe, MD, MMSc, MPH

Dr. Maduekwe will present an exploration of the dispersion of new therapies in the care of cancer that are inequitably distributed and solutions to closing these gaps.

To learn more and register, visit the webinar page.

Please note: Registration for the full webinar series is required.

Carolina Seminar Series | Empowering Trust: Insights from Community Engagement Initiatives

Empowering Trust: Insights from Community Engagement Initiatives

Wednesday, November 8 | 4 p.m. ET | Online

Speaker: Mya Roberson, MSPH, PhD,
Assistant Professor, Department of Health Policy and Management, UNC-Chapel Hill

Community engagement continues to be a critical component in genomic medicine and precision health research where the overall goal is to improve health outcomes of communities.  The translation of findings into practice and implementation depends heavily on stakeholder engagement throughout the research process. This seminar session will explore insights gained from various engagement strategies and how appropriate incorporation of community stakeholders’ insights can improve the relevance and usefulness of genomic medicine and precision health research.  Speakers and panelists will share their perspectives on community engagement, discuss strategies to address the gaps that remain and how to address the challenge of hesitancy among some communities.

To learn more and register, visit the UNC events page.

Please note: Registration is required for this seminar.

Cystic Fibrosis: Precision Treatment of a Rare Monogenic Disease

Wednesday, October 4 | 3 – 5 p.m. ET | Online

Join the UNC Program for Precision Medicine in Healthcare (PPMH) for Cystic Fibrosis: Precision Treatment of a Rare Monogenic Disease, a free virtual mini-symposium. At this interactive event, participants will engage in discussion with leading precision nutrition researchers at UNC.

Presentation: Developing small-molecule therapies to rescue rare CFTR variants
Speaker:
Rhianna Lee, PhD
Postdoctoral associate, Duke University, Cell Biology Department

Presentation: Personalized medicine, the fight against antibiotic resistance, and precision dosing
Speaker:
Gauri Rao, PharmD
Associate Professor, USC Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California
Adjunct Associate Professor, UNC Eshelman School of Pharmacy, UNC Chapel Hill

Presentation: From Data to Dosing: Streamlining CF Modulator Choices
Speaker:
Michael Adams, MD
Clinical Instructor, Division of Genetics & Metabolism, Department of Pediatrics, UNC School of Medicine

Learn more and register on the PPMH website.

Rapid Genome Sequencing for Diagnosing Critically Ill Infants and Children: From Evidence to Equitable Implementation

Rapid Genome Sequencing for Diagnosing Critically Ill Infants and Children: From Evidence to Equitable Implementation

Thursday, November 30 | 12-1 p.m. ET | Online

Speakers: Dr. Stephen F. Kingsmore, president/CEO of Rady Children’s Institute for Genomic Medicine (RCIGM)

To learn more and register, visit the CDC event page.

Please note: Registration is required for this webinar.

Clinician adherence to pharmacogenomics prescribing recommendations in clinical decision support alerts

Posted on by Alexis

Jenny Q Nguyen, Kristine R Crews, Ben T Moore, Nancy M Kornegay, Donald K Baker, Murad Hasan, Patrick K Campbell, Shannon M Dean, Mary V Relling , James M Hoffman, Cyrine E Haidar

Abstract

Thoughtful integration of interruptive clinical decision support (CDS) alerts within the electronic health record is essential to guide clinicians on the application of pharmacogenomic results at point of care. St. Jude Children’s Research Hospital implemented a preemptive pharmacogenomic testing program in 2011 in a multidisciplinary effort involving extensive education to clinicians about pharmacogenomic implications. We conducted a retrospective analysis of clinicians’ adherence to 4783 pharmacogenomically guided CDS alerts that triggered for 12 genes and 60 drugs. Clinicians adhered to the therapeutic recommendations provided in 4392 alerts (92%). In our population of pediatric patients with catastrophic illnesses, the most frequently presented gene/drug CDS alerts were TPMT/NUDT15 and thiopurines (n = 3850), CYP2D6 and ondansetron (n = 667), CYP2D6 and oxycodone (n = 99), G6PD and G6PD high-risk medications (n = 51), and CYP2C19 and proton pump inhibitors (omeprazole and pantoprazole; n = 50). The high adherence rate was facilitated by our team approach to prescribing and our collaborative CDS design and delivery.

Keywords: clinical decision support; medication alert systems; pharmacogenetics; pharmacogenomics; precision medicine.

Duke Precision Medicine Program Forum Series

Thursday, May 25 | 12-1 p.m. ET | Online

The Duke Precision Medicine Program Forum Series features speakers from Duke and beyond working on innovative research in clinical, translational, and basic sciences.

Katherine Collins, PhD
Postdoctoral Associate
Duke Molecular Physiology Institute
Precision Medicine Program T32

Title: Factors predicting who will stick with a lifestyle intervention: Utilizing precision medicine to improve healthy lifestyle behaviors

Learn more and register on the Precision Medicine Forum Series website.