Data and Safety Monitoring Board (DSMB)

The DSMB is responsible for safeguarding the interests of trial participants by assessing the safety and efficacy of the interventions during the trial, and for monitoring the overall conduct and progress of the trial to ensure that the results will be interpretable and of value to medical practice. The DSMB provides recommendations to the Division of Genomic Medicine (DGM), National Human Genome Research Institute (NHGRI), NIH about stopping, continuing, or making modifications to the trial to enhance the safety of trial participants, the value of the information collected, and/or to protect the integrity of the trial.

Members

DSMB Chair:

Bruce Korf, M.D., Ph.D.
University of Alabama                                                       

DSMB Members:

Timothy Thornton, Ph.D.
University of Washington

James Neaton, Ph.D.
University of Minnesota

Stephen Wisniewski, Ph.D.
Pittsburgh University

Mary Relling, PharmD
St. Jude

Karen Johnson, M.D., MPH
University of Tennessee Health Science Center

Peter O'Donnell, M.D.
University of Chicago

Jordan Smoller, M.D., Sc.D.
Massachusetts General Hospital

Executive Secretary:                 

Simona Volpi, PharmD, Ph.D.
Program Director
Division of Genomic Medicine
NHGRI

NHGRI ex officio members:

Teri Manolio, M.D., Ph.D.
Director
Division of Genomic Medicine
NHGRI

Ebony Madden, Ph.D.
Program Director
Division of Genomic Medicine
NHGRI

Sylvia Garvey, MPH, CPH
Scientific Program Specialist
Division of Genomic Medicine
NHGRI

Nicole Lockhart, Ph.D.
Program Director
Division of Genomes and Society
NHGRI

Michelle Cohen
Scientific Program Analyst
Division of Genomic Medicine
NHGRI