Data and Safety Monitoring Board (DSMB)

The DSMB is responsible for safeguarding the interests of trial participants by assessing the safety and efficacy of the interventions during the trial, and for monitoring the overall conduct and progress of the trial to ensure that the results will be interpretable and of value to medical practice. The DSMB provides recommendations to the Division of Genomic Medicine (DGM), National Human Genome Research Institute (NHGRI), NIH about stopping, continuing, or making modifications to the trial to enhance the safety of trial participants, the value of the information collected, and/or to protect the integrity of the trial.

Members

DSMB Chair:

Wendy Chung, MD
Columbia University

DSMB Members:

Timothy Thornton, PhD
University of Washington

James Neaton, PhD
University of Minnesota

Mary Relling, PharmD
St. Jude

Karen Johnson, MD, MPH
University of Tennessee Health Science Center

Peter O'Donnell, MD
University of Chicago

Jordan Smoller, MD, ScD
Massachusetts General Hospital

David Mauger, PhD
Pennsylvania State University

Executive Secretary:                 

Simona Volpi, PharmD, PhD
Program Director
Division of Genomic Medicine
NHGRI

NHGRI ex officio Member:

Teri Manolio, MD, PhD
Director
Division of Genomic Medicine
NHGRI